Reagent Kits for Quality Control Departments of Pharmaceutical Companies

Control of Heparin in Pharmaceuticals and Substances

1. Chromogenic methods according to the Russian Pharmacopoeia XIII and the European Pharmacopoeia 8.0: A) Renaparin test: Reagent kit for determining anti-Xa and anti-IIa activity of low-molecular-weight heparin; B) Renaparin-NFG test: Reagent kit for determining anti-Xa and anti-IIa activity of unfractionated heparin.

2. Clotting methods according to the Russian Pharmacopoeia XIII: Reagents for determining the activity of unfractionated heparin:

   • APTT-NFG reagent;
   • 0.025 M calcium chloride solution;
   • Working Standard Sample of unfractionated heparin.

3. Reagent kit for determining sodium citrate in anticoagulants.

Determination of the activity of plasma preparations

1. Clotting methods for determining the activity of coagulation factors: A) Substrate-deficient plasmas for: — Factor II, — Factor VII, — Factor VIII, — Factor IX, — Factor X. B) Coagulo-test; C) Renamplastin.

2. Reagent kit for determining the activity of antithrombin III.

3. Reagent kit for determining the concentration of fibrinogen.

4. Reagent kit for determining the activity of thrombin.

Working Standard Samples of Activity

1. Factor VIII;
2. Factor IX;
3. Antithrombin III;
4. Fibrinogen;
5. Thrombin.