In bioprinting, hydrogels are the primary type of 'bioink,' serving as the framework for cells. One of the most promising materials in bioprinting is fibrin, as, on one hand, cells embedded in it demonstrate high viability for an extended period (several weeks), and on the other hand, it possesses the necessary physical characteristics for creating three-dimensional structures with complex geometries. The main advantages of fibrin include its biocompatibility and acceptable rate of biodegradation.
The chemical polymerization (hardening) method is employed for printing with fibrin: fibrinogen and thrombin are mixed before or directly during the printing process. Using this material, tissue-engineered constructs have been printed with various cell types for the regeneration of cartilage tissue, skin, blood vessels, and liver tissue on models with corresponding defects in laboratory animals.
RENAM Research and Production Company reagents for bioprinting:
In bioprinting, hydrogels are the primary type of 'bioink,' serving as the framework for cells. One of the most promising materials in bioprinting is fibrin, as, on one hand, cells embedded in it demonstrate high viability for an extended period (several weeks), and on the other hand, it possesses the necessary physical characteristics for creating three-dimensional structures with complex geometries. The main advantages of fibrin include its biocompatibility and acceptable rate of biodegradation.
