Control plasma

Reagent for the control of the correctness of determining the parameters of the coagulation, anticoagulation, and fibrinolytic systems (Control plasma) according to TU 9398-026-05595541-2009.

Control plasma is intended for daily intralaboratory control of the correctness and reproducibility of the reagent-analyzer system when determining hemostasis indicators in normal and pathological ranges:

• Prothrombin in % according to Quick;
• International Normalized Ratio (INR);
• APTT in seconds;
• Thrombin time in seconds;
• Fibrinogen content according to Clauss, in g/L;
• Activity of internal pathway factors VIII, IX, XI, and XII in %;
• Activity of external and common pathway factors II, VII, and X in %;
• Activity of factor XIII in %;
• von Willebrand factor activity in %;
• Antithrombin III activity in %;
• Protein C activity in %;
• Plasminogen activity in %;
• Plasmin inhibitor activity in %.

Control plasma is designed to work both manually and on all types of semi-automatic and automatic coagulometers.

Method principle: Control plasma is analyzed in one series of measurements with the test plasma when performing tests for prothrombin time, APTT, thrombin time, determination of fibrinogen concentration, activity of coagulation factors II, VII, VIII, IX, X, XI, XII, XIII, and von Willebrand factor (vWF), ATIII activity, protein C, plasminogen, and plasmin inhibitor according to the instructions accompanying the respective reagent kits. The analyzed parameters of the control material should fall within the range of values specified in the kit's passport.