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Thrombin test

The set of reagents for determining thrombin time (Thrombin test) according to TU 9398-255-05595541-2010 is intended for coagulological determination of thrombin time in blood plasma, both manually and on all types of semi-automatic and automatic coagulometers.

The thrombin time test is designed to assess the final stage of blood clotting, i.e., the speed of transformation of fibrinogen into fibrin. It is used to determine the functional activity of fibrinogen and thrombin inhibitors in plasma, such as:

  • Products of fibrin/fibrinogen degradation.
  • Heparin and heparinoids.
  • During fibrinolytic therapy.

Method principle: The method is based on determining the time of fibrin clot formation by adding a solution of thrombin of the required activity to the plasma.

Translation into English:

A set of reagents for thrombin time determination (Thrombin test) according to TU 9398-255-05595541-2010 is designed for coagulological assessment of thrombin time in blood plasma, both manually and on all types of semi-automatic and automatic coagulometers.

The thrombin time test is intended for evaluating the final stage of blood clotting, i.e., the speed of transforming fibrinogen into fibrin, and for determining the functional activity of fibrinogen and thrombin inhibitors in plasma, such as:

  • Products of fibrin/fibrinogen degradation.
  • Heparin and heparinoids.
  • During fibrinolytic therapy.

Method principle: The method is based on determining the time of fibrin clot formation by adding a solution of thrombin of the required activity to the plasma.

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Composition of the kit:

  • Thrombin for thrombin time determination – 2 vials;
  • Stabilizer (ethylene glycol) – 1 vial.

With an expenditure of 0.1 ml of thrombin per analysis, the kit is intended for conducting:

  • Not less than 150 analyses with thrombin activity of 9 IU/ml, or
  • Not less than 200 analyses with thrombin activity of 6 IU/ml, or
  • Not less than 400 analyses with thrombin activity of 3 IU/ml.

Normal and pathological values of thrombin time should be monitored using Control Plasma (pool of healthy donors) (Plasma N), code KM-1.

Translation into English:

Composition of the kit:

  • Thrombin for thrombin time determination – 2 vials;
  • Stabilizer (ethylene glycol) – 1 vial.

With an expenditure of 0.1 ml of thrombin per analysis, the kit is intended for conducting:

  • Not less than 150 analyses with thrombin activity of 9 IU/ml, or
  • Not less than 200 analyses with thrombin activity of 6 IU/ml, or
  • Not less than 400 analyses with thrombin activity of 3 IU/ml.

Normal and pathological values of thrombin time should be monitored using Control Plasma (pool of healthy donors) (Plasma N), code KM-1.