PG-3/2
Registration CertificateReagent for prothrombin time determination by clotting method (recombinant human thromboplastin in a mixture with calcium chloride in a buffer with stabilizers) according to RC 21.20.23-077-05595541-2025 " ("Replastin").
The Replastin is designed to determine the prothrombin time (PT) in blood plasma in order to study the activity of prothrombin complex factors, liver function, and to assess the effectiveness of oral anticoagulants.
ISI=1.0-1.2.
Replastin is designed to work on all types of semi-automatic and automatic coagulometers and by manual method.
The principle of the method:
When added to the citrated plasma, an excess of tissue thromboplastin and calcium ions results in the formation of a fibrin clot. The time from adding the thromboplastin-calcium ion mixture to the investigated plasma to the formation of the fibrin clot depends solely on the activity of factors in the external and common pathways of coagulation: I, II, V, VII, X.
The composition of the sets:
Replastin, liquid – volume 5.0 ml/bottle — 10 bottles.
1 bottle of liquid Replastin is designed to carry out 50 determinations. 1 set - 500 determinations.
Normal and pathological values of the studied hemostasis parameters should be monitored using Prothrombin control, KM-17 or using Control plasma (pool of healthy donors) (Plasma N), KM-1.
