The Diagem P kit is designed for determining the prothrombin time (PT) in venous blood plasma and calculating the prothrombin ratio (PR), prothrombin index (PI), and International Normalized Ratio (INR). It is also used for determining prothrombin according to Quick in % of the norm.
Prothrombin time determination is a highly sensitive and simple screening test that detects abnormalities in the extrinsic and common pathways of blood coagulation (Factors II, V, VII, and X). It is recommended for:
The Diagem P kit is intended for use on all types of semi-automatic and automatic coagulometers, as well as for manual methods.
Method principle: Upon adding an excess of tissue thromboplastin and calcium ions to citrate plasma, the fibrin clot formation time depends only on the activity of factors in the extrinsic and common coagulation pathways: I, II, V, VII, X. The time is determined from the moment of adding the thromboplastin and calcium ion mixture to the investigated plasma until the formation of the fibrin clot.
The Diagem P kit includes:
One Diagem P kit is designed for conducting 300 analyses with a consumption of 0.1 ml of thromboplastin per analysis.
Normal and pathological values of prothrombin according to Quick and INR should be monitored using the Prothrombin Control kit, code KM-17, or Control Plasma (pool of healthy donors) (Plasma N), code KM-1.
